Uitstekende correlatie Serion Parvo Elisa met DiaSorin Biotrin Parvovirus B19 Elisa

Intro tekst

Uit recente studies is gebleken dat de Serion Parvo B19 Elisa een goed alternatief is voor de bekende Biotrin Parvo B19 Elisa.

Uit een interne vergelijking is gebleken dat de SERION ELISA Classic Parvovirus B19 IgG- en IgM-tests een zeer goede correlatie hebben met de DiaSorin Biotrin Parvovirus B19 IgG ELISA. De sensitiviteit bedraagt > 99% en een specificiteit van> 99%.

Afbeelding

SERION ELISA classic Parvovirus B19 IgG
The analyzed serum panel consisted of 230 serum samples:

• 103 sera from healthy blood donors
• 64 sera from pregnant women
• 14 sera from German EQAS (INSTAND e.V.)
• 14 internal Quality Control sera
• 35 sera from patients with suspected infection
 

The results revealed a very good agreement between SERION ELISA classic Parvovirus B19 IgG and DiaSorin Biotrin Parvovirus B19 IgG ELISA with a sensitivity of > 99 % and a specificity of > 99 %. 64 serum samples showed consistent negative results, two serum samples were concordantly evaluated borderline and in 156 samples IgG antibody activity could be detected by both
assays (see Table 1).

Table 1: Comparative evaluation of results obtained with
SERION ELISA classic Parvovirus B19 IgG and DiaSorin Biotrin Parvovirus B19 IgG ELISA
serion elisa parvo IgG.JPG

 

SERION ELISA classic Parvovirus B19 IgM
The analyzed serum panel consisted of 132 serum samples:

• 72 sera from healthy blood donors
• 60 sera from patients with suspected infection

 

Also for IgM a very good agreement between SERION ELISA classic Parvovirus B19 IgM and DiaSorin Biotrin Parvovirus B19 IgM with a sensitivity of > 99 % and a specificity of > 99 % could be observed. Negative results were found in 76 serum samples and antibody activity could be detected in 51 samples by both assays (see Table 2).

Table 2: Comparative evaluation of results obtained with
SERION ELISA classic Parvovirus B19 IgM and DiaSorin Biotrin Parvovirus B19 IgM ELISA
serion elisa parvo IgM.JPG

Please note that results in the borderline (bl) range were not considered for the calculation. The performance evaluation studies demonstrate a high diagnostic efficiency of the SERION ELISA classic Parvovirus B19 IgG and IgM immunoassays and a highly convincing correlation with the corresponding DiaSorin Biotrin Parvovirus B19 test.